Sebilangan besar kes gout dirawat dengan penggunaan ubat. Ubat dapat digunakan untuk mengubati gejala serangan gout, mencegah pengulangan keadaan sama di masa depan dan mengurangkan risiko komplikasi gout seperti batu karang dan perkembangan tophi.
Dos akan dinaikkan secara beransur-ansur sehingga mencapai paras asid urik yang disasarkan, iaitu kurang daripada six.0 mg/dL. Bagi pesakit dengan masalah buah pinggang, dos allopurinol dimulakan pada tahap yang rendah dan dipantau dengan teliti.
Rawatan akut sering memerlukan disiplin ubat yang ketat bersama dengan pengubahsuaian gaya hidup. Secara spesifik, semasa terapi gout akut, pengamal perubatan menetapkan ubat tertentu dan mengesyorkan pelan pemakanan sihat yang membantu mengurangkan tahap pengeluaran dan pengambilan asid urik.
Colchicine boleh diekskresikan ke dalam susu ibu. Namun, jumlah yang dipindahkan adalah kecil, dan kesannya terhadap bayi biasanya tidak signifikan. Walaupun begitu:
The pain from the gout attack commonly will get superior in three to 10 days. However , you'll truly feel much better faster with gout treatment. If you believe You may have it, Get hold of your medical professional. An Test and assessments will clearly show if It is really gout or something else, like an an infection.
Many drugs are successful for acute flare-ups. The effectiveness of low-dose colchicine is analogous to that of higher-dose colchicine with much less adverse results. NSAIDs and glucocorticoids are as productive as colchicine.
If you expertise unexpected, intense pain inside a joint, see your physician to get a analysis. Gout that's not dealt with could cause irreversible joint destruction, kidney stones and the development of tophi.
Reducing down on sugary drinks and Liquor might also enable reduce flares. On the gout ubat other hand, understand that dietary adjustments with medicines are helpful.
Pegloticase (Krystexxa) is another choice to reduced manufacture of uric acid. It is generally reserved for Individuals who have critical gout and have not experienced success with other treatments or are not able to tolerate them. This medication is provided intravenously every 2 months in conjunction with weekly oral methotrexate to forestall Unwanted effects and enhance usefulness.
Reduce or simply reduce your intake of meat and shellfish, both of which often can elevate uric acid levels.
Uric acid can be a squander solution that is certainly shaped when purines - critical substances located in protein and various foods - are damaged down. Underneath usual disorders, uric acid dissolves in the blood, passes through the kidneys, and is also excreted during the urine. Not so in individuals with gout.
Probenecid may very well be applied by itself or combined with allopurinol or febuxostat in persons whose uric acid ranges don't slide adequate with just allopurinol or febuxostat.
Urate-Decreasing Drugs Urate-reducing drugs are used to enable manage chronic gout and prevent flares. They may be encouraged for Individuals who have at the very least two gout flares every year and people with troubles like tophi.
Colchicine interacts with other medicines broken down because of the liver enzyme cytochrome P450 3A4. A number of examples include things like statins, antifungals, and several coronary heart medicines.